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Acute fasting inhibits central caspase-1 activity reducing anxiety-like behavior and increasing novel object and object location recognition
BACKGROUND: Inflammation within the central nervous system (CNS) is frequently comorbid with anxiety. Importantly, the pro-inflammatory cytokine most commonly associated with anxiety is IL-1β. The bioavailability and activity of IL-1β is regulated by caspase-1-dependent proteolysis vis-a-vis the inf...
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| Publicado no: | Metabolism |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5439304/ https://ncbi.nlm.nih.gov/pubmed/28521881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2017.03.005 |
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