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AGO2 Negatively Regulates Type I Interferon Signaling Pathway by Competition Binding IRF3 with CBP/p300

Viral infection triggers a series of signaling cascades and host innate immune responses, including interferon (IFN) production, which depends on coordinated activity of multiple transcription factors. IFN regulatory factor 3 (IRF3) and transcriptional coactivator CREB binding protein (CBP) and/or p...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Wang, Shengyu, Sun, Xin, Yi, Chenyang, Zhang, Dan, Lin, Xian, Sun, Xiaomei, Chen, Huanchun, Jin, Meilin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438986/
https://ncbi.nlm.nih.gov/pubmed/28589097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00195
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