E6 and E7 antibody levels are potential biomarkers of recurrence in patients with advanced stage human papillomavirus positive oropharyngeal squamous cell carcinoma

BACKGROUND: There is a paucity of biomarkers to predict failure in human papilloma-virus positive (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) following curative therapy. E6/E7 viral oncoproteins are constitutively expressed in HPV+ tumors and highly immunogenic, resulting in readily detecte...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Spector, Matthew E., Sacco, Assuntina G., Bellile, Emily, Taylor, Jeremy M. G., Jones, Tamara, Sun, Kan, Brown, William C., Birkeland, Andrew C., Bradford, Carol R., Wolf, Gregory T., Prince, Mark E., Moyer, Jeffrey S., Malloy, Kelly, Swiecicki, Paul, Eisbruch, Avraham, McHugh, Jonathan B, Chepeha, Douglas B., Rozek, Laura, Worden, Francis P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438906/
https://ncbi.nlm.nih.gov/pubmed/27872102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1617
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