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Sex Differences in the Blood Concentration of Tacrolimus in Systemic Lupus Erythematosus and Rheumatoid Arthritis Patients with CYP3A5*3/*3

The purpose of this study was to describe the impact of sex and cytochrome P450 3A5 (CYP3A5) variant on the blood concentration of tacrolimus in patients with systemic lupus erythematosus or rheumatoid arthritis. The blood concentration of tacrolimus (ng/mL) divided by the daily dose of tacrolimus (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochem Genet
Hauptverfasser: Ito, Ayano, Okada, Yuko, Hashita, Tadahiro, Aomori, Tohru, Hiromura, Keiju, Nojima, Yoshihisa, Nakamura, Tomonori, Araki, Takuya, Yamamoto, Koujirou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438821/
https://ncbi.nlm.nih.gov/pubmed/28324194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10528-017-9795-8
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