Bone marrow-derived mesenchymal stem cells overexpressing miR-21 efficiently repair myocardial damage in rats

OBJECTIVE: We investigated the ability of bone marrow derived mesenchymal stem cells (BMSCs) overexpressing microRNA-21 (miR-21) to repair cardiac damage induced by anthracyclines in rats. METHODS: Sprague-Dawley (SD) rats of 2~3 weeks old were selected to isolate and culture BMSCs. A lentivirus har...

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Pubblicato in:Oncotarget
Autori principali: Zeng, Yan-Ling, Zheng, Hao, Chen, Qiu-Ru, Yuan, Xiao-Hong, Ren, Jin-Hua, Luo, Xiao-Feng, Chen, Ping, Lin, Zhe-Yao, Chen, Shao-Zhen, Wu, Xue-Qiong, Xiao, Min, Chen, Yong-Quan, Chen, Zhi-Zhe, Hu, Jian-Da, Yang, Ting
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438721/
https://ncbi.nlm.nih.gov/pubmed/28418864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16254
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