Expression of HIF-1α in medullary thyroid cancer identifies a subgroup with poor prognosis

BACKGROUND: Medullary thyroid cancer (MTC) comprises only 4% of all thyroid cancers and originates from the parafollicular C-cells. HIF-1α expression has been implied as an indicator of worse prognosis in various solid tumors. However, whether expression of HIF-1α is a prognosticator in MTC remained...

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Udgivet i:Oncotarget
Main Authors: Lodewijk, Lutske, van Diest, Paul, van der Groep, Petra, ter Hoeve, Natalie, Schepers, Abbey, Morreau, Johannes, Bonenkamp, Johannes, van Engen - van Grunsven, Adriana, Kruijff, Schelto, van Hemel, Bettien, Links, Thera, van Dijkum, Els Nieveen, van Eeden, Susanne, Valk, Gerlof, Rinkes, Inne Borel, Vriens, Menno
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438680/
https://ncbi.nlm.nih.gov/pubmed/28404916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15622
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