MeDIP-seq and nCpG analyses illuminate sexually dimorphic methylation of gonadal development genes with high historic methylation in turtle hatchlings with temperature-dependent sex determination

BACKGROUND: DNA methylation alters gene expression but not DNA sequence and mediates some cases of phenotypic plasticity. Temperature-dependent sex determination (TSD) epitomizes phenotypic plasticity where environmental temperature drives embryonic sexual fate, as occurs commonly in turtles. Import...

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Publicado en:Epigenetics Chromatin
Autores principales: Radhakrishnan, Srihari, Literman, Robert, Mizoguchi, Beatriz, Valenzuela, Nicole
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438563/
https://ncbi.nlm.nih.gov/pubmed/28533820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-017-0136-2
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