The Anti-Amyloid-β and Neuroprotective Properties of a Novel Tricyclic Pyrone Molecule

There is an urgent unmet need for new therapeutics for Alzheimer’s disease (AD), the most common cause of dementia in the elderly. Therapeutic approaches targeting amyloid-β (Aβ) and its downstream toxicities have become major strategies in AD drug development. We have taken a rational design approa...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Maezawa, Izumi, Zou, Bende, Di Lucente, Jacopo, Cao, William S., Pascual, Conrado, Weerasekara, Sahani, Zhang, Man, Xie, Xinmin Simon, Hua, Duy H., Jin, Lee-Way
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438482/
https://ncbi.nlm.nih.gov/pubmed/28482635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-161175
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