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Early inflammatory changes in radiation-induced oral mucositis: Effect of pentoxifylline in a mouse model

PURPOSE: Early inflammation is a major factor of mucosal reactions to radiotherapy. Pentoxifylline administration resulted in a significant amelioration of radiation-induced oral mucositis in the mouse tongue model. The underlying mechanisms may be related to the immunomodulatory properties of the d...

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Bibliographic Details
Published in:Strahlenther Onkol
Main Authors: Gruber, Sylvia, Bozsaky, Eva, Roitinger, Eva, Schwarz, Karoline, Schmidt, Margret, Dörr, Wolfgang
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438416/
https://ncbi.nlm.nih.gov/pubmed/28258409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00066-017-1119-8
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