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FK866 attenuates acute hepatic failure through c-jun-N-terminal kinase (JNK)-dependent autophagy
FK866 exhibits a protective effect on D-galactosamine (GaIN)/lipopolysaccharide (LPS) and concanavalin A (ConA)-induced acute liver failure (ALF), but the mechanism by which FK866 affords this benefit has not yet been elucidated. Autophagy has a protective effect on acute liver injury. However, the...
Tallennettuna:
| Julkaisussa: | Sci Rep |
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| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5438370/ https://ncbi.nlm.nih.gov/pubmed/28526886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02318-7 |
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