FK866 attenuates acute hepatic failure through c-jun-N-terminal kinase (JNK)-dependent autophagy

FK866 exhibits a protective effect on D-galactosamine (GaIN)/lipopolysaccharide (LPS) and concanavalin A (ConA)-induced acute liver failure (ALF), but the mechanism by which FK866 affords this benefit has not yet been elucidated. Autophagy has a protective effect on acute liver injury. However, the...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Guo, Enshuang, Li, Renlong, Yang, Jiankun, Zhang, Jun, Li, Anyi, Yang, Yan, Liu, Shenpei, Liu, Anding, Jiang, Xiaojing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438370/
https://ncbi.nlm.nih.gov/pubmed/28526886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02318-7
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