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Aggregation Effects and Population-based dynamics as a source of therapy resistance in cancer

OBJECTIVE: Evolution of resistance allows cancer cells to adapt and continue proliferating even when therapy is initially very effective. Most investigations of treatment resistance focus on the adaptive phenotypic properties of individual cells. We propose that the resistance of a single cell to th...

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書目詳細資料
發表在:IEEE Trans Biomed Eng
Main Authors: Brown, Joel S., Cunningham, Jessica J., Gatenby, Robert A.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438296/
https://ncbi.nlm.nih.gov/pubmed/28113286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TBME.2016.2623564
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