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Ipilimumab as a Cause of Severe Pan-Colitis and Colonic Perforation

Ipilimumab is a human monoclonal antibody that functions as a cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) inhibitor that is used to treat malignant melanoma. Due to ipilimumab’s removal of immune regulation, specifically through the inactivation of CTLA-4, it is commonly associated with inf...

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Detalhes bibliográficos
Publicado no:Cureus
Main Authors: Shah, Raj, Witt, Danielle, Asif, Talal, Mir, Fahad F
Formato: Artigo
Idioma:Inglês
Publicado em: Cureus 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438238/
https://ncbi.nlm.nih.gov/pubmed/28533998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.1182
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