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DNA methylation as a putative mechanism for reduced dendritic spine density in the superior temporal gyrus of subjects with schizophrenia

Reduced dendritic spine density (DSD) in cortical layer 3 of the superior temporal gyrus (STG), and multiple other brain regions, is consistently observed in postmortem studies of schizophrenia (SZ). Elucidating the molecular mechanisms of this intermediate phenotype holds promise for understanding...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: McKinney, B, Ding, Y, Lewis, D A, Sweet, R A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438028/
https://ncbi.nlm.nih.gov/pubmed/28195572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.297
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