The evolution of no-cost resistance at sub-MIC concentrations of streptomycin in Streptomyces coelicolor

At the high concentrations used in medicine, antibiotics exert strong selection on bacterial populations for the evolution of resistance. However, these lethal concentrations may not be representative of the concentrations bacteria face in soil, a recognition that has led to questions of the role of...

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Bibliographic Details
Published in:ISME J
Main Authors: Westhoff, Sanne, van Leeuwe, Tim Marijn, Qachach, Omar, Zhang, Zheren, van Wezel, Gilles Philippus, Rozen, Daniel Eric
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437928/
https://ncbi.nlm.nih.gov/pubmed/28094796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ismej.2016.194
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