Two novel BMP-2 variants identified in patients with thoracic ossification of the ligamentum flavum

Thoracic ossification of the ligamentum flavum (TOLF)is a common cause of thoracic spinal canal stenosis and has been reported almost exclusively in East Asian countries. In this study, we established a relationship between bone morphogenic protein 2 (BMP-2) and TOLF. We divided patients into two gr...

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Vydáno v:Eur J Hum Genet
Hlavní autoři: Qu, Xiaochen, Chen, Zhongqiang, Fan, Dongwei, Xiang, Shen, Sun, Chuiguo, Zeng, Yan, Li, Weishi, Guo, Zhaoqing, Qi, Qiang, Zhong, Woquan, Jiang, Yun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437907/
https://ncbi.nlm.nih.gov/pubmed/28145426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2017.2
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