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Macrophage-colony-stimulating factor (CSF-1) induces proliferation, chemotaxis, and reversible monocytic differentiation in myeloid progenitor cells transfected with the human c-fms/CSF-1 receptor cDNA.

The c-fms protooncogene encodes the receptor for macrophage-colony-stimulating factor (CSF-1). Expression vectors containing either normal or oncogenic point-mutated human c-fms genes were transfected into interleukin 3 (IL-3)-dependent 32D cells in order to determine the effects of CSF-1 signaling...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Pierce, J H, Di Marco, E, Cox, G W, Lombardi, D, Ruggiero, M, Varesio, L, Wang, L M, Choudhury, G G, Sakaguchi, A Y, Di Fiore, P P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54377/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2165597/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.15.5613
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