M2 macrophage is the predominant phenotype in airways inflammatory lesions in patients with granulomatosis with polyangiitis

BACKGROUND: Macrophages may present two distinct phenotypes indicated as M1 and M2 under different stimuli. M1 and M2 macrophages have divergent functions that range from enhancement of inflammation for M1 to tissue repair and remodeling for M2 macrophages. The objective of this study was to evaluat...

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Publicado en:Arthritis Res Ther
Main Authors: de Souza, Alexandre Wagner Silva, van Timmeren, Mirjan, Sanders, Jan-Stephan, Stegeman, Coen, Heeringa, Peter, Kallenberg, Cees G. M., Westra, Johanna
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437644/
https://ncbi.nlm.nih.gov/pubmed/28521792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1310-4
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