Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania

The indigenous populations of the South Pacific experience a high burden of rheumatic heart disease (RHD). Here we report a genome-wide association study (GWAS) of RHD susceptibility in 2,852 individuals recruited in eight Oceanian countries. Stratifying by ancestry, we analysed genotyped and impute...

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Publicado en:Nat Commun
Main Authors: Parks, Tom, Mirabel, Mariana M., Kado, Joseph, Auckland, Kathryn, Nowak, Jaroslaw, Rautanen, Anna, Mentzer, Alexander J., Marijon, Eloi, Jouven, Xavier, Perman, Mai Ling, Cua, Tuliana, Kauwe, John K., Allen, John B., Taylor, Henry, Robson, Kathryn J., Deane, Charlotte M., Steer, Andrew C., Hill, Adrian V. S.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437274/
https://ncbi.nlm.nih.gov/pubmed/28492228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14946
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