ISCA1 is essential for mitochondrial Fe(4)S(4) biogenesis in vivo

Mammalian A-type proteins, ISCA1 and ISCA2, are evolutionarily conserved proteins involved in iron–sulfur cluster (Fe–S) biogenesis. Recently, it was shown that ISCA1 and ISCA2 form a heterocomplex that is implicated in the maturation of mitochondrial Fe(4)S(4) proteins. Here we report that mouse IS...

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Pubblicato in:Nat Commun
Autori principali: Beilschmidt, Lena Kristina, Ollagnier de Choudens, Sandrine, Fournier, Marjorie, Sanakis, Ioannis, Hograindleur, Marc-André, Clémancey, Martin, Blondin, Geneviève, Schmucker, Stéphane, Eisenmann, Aurélie, Weiss, Amélie, Koebel, Pascale, Messaddeq, Nadia, Puccio, Hélène, Martelli, Alain
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437272/
https://ncbi.nlm.nih.gov/pubmed/28492233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15124
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