C. elegans chromosomes connect to centrosomes by anchoring into the spindle network

The mitotic spindle ensures the faithful segregation of chromosomes. Here we combine the first large-scale serial electron tomography of whole mitotic spindles in early C. elegans embryos with live-cell imaging to reconstruct all microtubules in 3D and identify their plus- and minus-ends. We classif...

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Published in:Nat Commun
Main Authors: Redemann, Stefanie, Baumgart, Johannes, Lindow, Norbert, Shelley, Michael, Nazockdast, Ehssan, Kratz, Andrea, Prohaska, Steffen, Brugués, Jan, Fürthauer, Sebastian, Müller-Reichert, Thomas
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437269/
https://ncbi.nlm.nih.gov/pubmed/28492281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15288
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