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Insights into Rad3 kinase recruitment from the crystal structure of the DNA damage checkpoint protein Rad26

Metabolic products and environmental factors constantly damage DNA. To protect against these insults and maintain genome integrity, cells have evolved mechanisms to repair DNA lesions. One such mechanism involves Rad3, a master kinase coordinating the DNA damage response. Rad26 is a functional subun...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Autor principal: Andersen, Kasper Røjkjær
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437224/
https://ncbi.nlm.nih.gov/pubmed/28314775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.780189
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