Acute Simian Immunodeficiency Virus Infection Triggers Early and Transient Interleukin-7 Production in the Gut, Leading to Enhanced Local Chemokine Expression and Intestinal Immune Cell Homing

The intestinal barrier, one of the first targets of HIV/simian immunodeficiency virus (SIV) is subjected to major physiological changes during acute infection. Having previously shown that pharmaceutical injection of interleukin-7 (IL-7) triggers chemokine expression in many organs leading to massiv...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Ponte, Rosalie, Rancez, Magali, Figueiredo-Morgado, Suzanne, Dutrieux, Jacques, Fabre-Mersseman, Véronique, Charmeteau-de-Muylder, Bénédicte, Guilbert, Thomas, Routy, Jean-Pierre, Cheynier, Rémi, Couëdel-Courteille, Anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437214/
https://ncbi.nlm.nih.gov/pubmed/28579989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00588
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