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Role of treatment-modifying MTHFR677C>T and 1298A > C polymorphisms in metformin-treated Puerto Rican patients with type-2 diabetes mellitus and peripheral neuropathy

BACKGROUND: The study was conducted to investigate potential association between MTHFR genotypes and diabetic peripheral neuropathy (DPN) in Puerto Ricans with type-2 diabetes mellitus (T2DM) treated with metformin. The prevalence of major MTHFR polymorphisms in this cohort was also ascertained. MET...

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Detalhes bibliográficos
Publicado no:Drug Metab Pers Ther
Main Authors: Jiménez-Ramírez, Francisco J., Castro, Liza M., Ortiz, Clarymar, Concepción, Jennifer, Renta, Jessicca Y., Morales-Borges, Raúl H., Miranda-Massari, Jorge R., Duconge, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436794/
https://ncbi.nlm.nih.gov/pubmed/28231061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/dmpt-2016-0039
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