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Corticosterone oscillations during mania induction in the lateral hypothalamic kindled rat—Experimental observations and mathematical modeling

Changes in the hypothalamic-pituitary-adrenal (HPA) axis activity constitute a key component of bipolar mania, but the extent and nature of these alterations are not fully understood. We use here the lateral hypothalamic-kindled (LHK) rat model to deliberately induce an acute manic-like episode and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Abulseoud, Osama A., Ho, Man Choi, Choi, Doo-Sup, Stanojević, Ana, Čupić, Željko, Kolar-Anić, Ljiljana, Vukojević, Vladana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436765/
https://ncbi.nlm.nih.gov/pubmed/28542167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177551
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