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Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1

AIMS: Remodelling of gap junctions, involving reduction of total gap junction quantity and down-regulation of connexin43 (Cx43), contributes to the arrhythmic substrate in congestive heart failure. However, little is known of the underlying mechanisms. Recent studies from in vitro systems suggest th...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Bruce, Alexandra F., Rothery, Stephen, Dupont, Emmanuel, Severs, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436744/
https://ncbi.nlm.nih.gov/pubmed/18056766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvm083
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