Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia

[Image: see text] Postmortem brain studies support dysregulated expression of the histone deacetylase enzymes, HDAC1 and HDAC2, as a central feature in diseases including schizophrenia, bipolar disorder, and depression. Our objective was to investigate HDAC expression in a large postmortem sample se...

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Bibliographic Details
Published in:ACS Chem Neurosci
Main Authors: Schroeder, Frederick A., Gilbert, Tonya M., Feng, Ningping, Taillon, Brendan D., Volkow, Nora D., Innis, Robert B., Hooker, Jacob M., Lipska, Barbara K.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2016
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436730/
https://ncbi.nlm.nih.gov/pubmed/27959513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.6b00372
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