Eculizumab Therapy in Children with Severe Hematopoietic Stem Cell Transplantation–Associated Thrombotic Microangiopathy

We recently observed that dysregulation of the complement system may be involved in the pathogenesis of hematopoietic stem cell transplantation–associated thrombotic microangiopathy (HSCT-TMA). These findings suggest that the complement inhibitor eculizumab could be a therapeutic option for this sev...

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Détails bibliographiques
Publié dans:Biol Blood Marrow Transplant
Auteurs principaux: Jodele, Sonata, Fukuda, Tsuyoshi, Vinks, Alexander, Mizuno, Kana, Laskin, Benjamin L., Goebel, Jens, Dixon, Bradley P., Teusink, Ashley, Pluthero, Fred G., Lu, Lily, Licht, Christoph, Davies, Stella M.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436705/
https://ncbi.nlm.nih.gov/pubmed/24370861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2013.12.565
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