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Deviant lysosomal Ca(2+) signalling in neurodegeneration. An introduction
Lysosomes are key acidic Ca(2+) stores. The principle Ca(2+)-permeable channels of the lysosome are TRP mucolipins (TRPMLs) and NAADP-regulated two-pore channels (TPCs). Recent studies, reviewed in this collection, have linked numerous neurodegenerative diseases to both gain and loss of function of...
Shranjeno v:
| izdano v: | Messenger (Los Angel) |
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| Glavni avtor: | |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436605/ https://ncbi.nlm.nih.gov/pubmed/28529827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1166/msr.2016.1053 |
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