Overexpression of Insulin-Like Growth Factor 1 Enhanced the Osteogenic Capability of Aging Bone Marrow Mesenchymal Stem Cells

Many studies have indicated that loss of the osteoblastogenic potential in bone marrow mesenchymal stem cells (bmMSCs) is the major component in the etiology of the aging-related bone deficit. But how the bmMSCs lose osteogenic capability in aging is unclear. Using 2-dimentional cultures, we examine...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Chen, Ching-Yun, Tseng, Kuo-Yun, Lai, Yen-Liang, Chen, Yo-Shen, Lin, Feng-Huei, Lin, Shankung
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436515/
https://ncbi.nlm.nih.gov/pubmed/28529639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.16637
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