Overexpression of Insulin-Like Growth Factor 1 Enhanced the Osteogenic Capability of Aging Bone Marrow Mesenchymal Stem Cells

Many studies have indicated that loss of the osteoblastogenic potential in bone marrow mesenchymal stem cells (bmMSCs) is the major component in the etiology of the aging-related bone deficit. But how the bmMSCs lose osteogenic capability in aging is unclear. Using 2-dimentional cultures, we examine...

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Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Chen, Ching-Yun, Tseng, Kuo-Yun, Lai, Yen-Liang, Chen, Yo-Shen, Lin, Feng-Huei, Lin, Shankung
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436515/
https://ncbi.nlm.nih.gov/pubmed/28529639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.16637
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