Vaccination with a live retrovirus: the nature of the protective immune response.

We tested 3'-azido-3'-deoxythymidine (zidovudine) combined with interferon alpha as chemoprophylaxis after exposing mice to Rauscher murine leukemia virus. Therapy started 4 hr after inoculation and administered for 20 days prevented viremia and disease in all 234 mice tested. When the animals were...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Ruprecht, R M, Mullaney, S, Bernard, L D, Gama Sosa, M A, Hom, R C, Finberg, R W
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54364/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2371289/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.14.5558
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