Complement C5a Receptor is the Key Initiator of Neutrophil Adhesion Igniting Immune Complex-induced Arthritis

The deposition of immune complexes (IC) in tissues induces a “type III hypersensitivity” that results in tissue damage and underlies the pathogenesis of many autoimmune diseases. The neutrophil is the first immune cell recruited into sites of IC deposition and plays a critical role in shaping the ov...

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Pubblicato in:Sci Immunol
Autori principali: Miyabe, Yoshishige, Miyabe, Chie, Murooka, Thomas T., Kim, Edward Y., Newton, Gail A., Kim, Nancy D., Haribabu, Bodduluri, Luscinskas, Francis W., Mempel, Thorsten R., Luster, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436313/
https://ncbi.nlm.nih.gov/pubmed/28529998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaj2195
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