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Functional and ultrastructural evidence for intracellular formation of major histocompatibility complex class II-peptide complexes during antigen processing.

Antigen presentation requires intracellular processing of native antigens to produce immunogenic peptides that bind to major histocompatibility complex class II (MHC-II) molecules. In functional studies of antigen processing by elicited peritoneal macrophages, MHC-II-peptide complexes were formed in...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Harding, C V, Unanue, E R, Slot, J W, Schwartz, A L, Geuze, H J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54363/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2371288/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.14.5553
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