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Single-Molecule Studies of the Linker Histone H1 Binding to DNA and the Nucleosome
Linker histone H1 regulates chromatin structure and gene expression. Investigating the dynamics and stoichiometry of binding of H1 to DNA and the nucleosome is crucial to elucidating its functions. Because of the abundant positive charges and the strong self-affinity of H1, quantitative in vitro stu...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436050/ https://ncbi.nlm.nih.gov/pubmed/27010485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01247 |
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