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Modeling complex patterns of differential DNA methylation that associate with gene expression changes

Numerous genomic studies are underway to determine which genes are abnormally regulated by DNA methylation in disease. However, we have a poor understanding of how disease-specific methylation changes affect expression. We thus developed an integrative analysis tool, Methylation-based Gene Expressio...

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Pubblicato in:Nucleic Acids Res
Autori principali: Schlosberg, Christopher E., VanderKraats, Nathan D., Edwards, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435975/
https://ncbi.nlm.nih.gov/pubmed/28168293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx078
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