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Regulation of DNA demethylation by the XPC DNA repair complex in somatic and pluripotent stem cells

Faithful resetting of the epigenetic memory of a somatic cell to a pluripotent state during cellular reprogramming requires DNA methylation to silence somatic gene expression and dynamic DNA demethylation to activate pluripotency gene transcription. The removal of methylated cytosines requires the b...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Ho, Jaclyn J., Cattoglio, Claudia, McSwiggen, David T., Tjian, Robert, Fong, Yick W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435894/
https://ncbi.nlm.nih.gov/pubmed/28512237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.295741.116
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