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Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression

Mitochondrial respiration plays a crucial role in determining the metabolic state of brown adipose tissue (BAT), due to its direct roles in thermogenesis, as well as through additional mechanisms. Here, we show that respiration-dependent retrograde signaling from mitochondria to nucleus contributes...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nam, Minwoo, Akie, Thomas E., Sanosaka, Masato, Craige, Siobhan M., Kant, Shashi, Keaney Jr, John F., Cooper, Marcus P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435730/
https://ncbi.nlm.nih.gov/pubmed/28515438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01879-x
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