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MiR-520b as a novel molecular target for suppressing stemness phenotype of head-neck cancer by inhibiting CD44

Cancer stem cells preferentially acquire the specific characteristics of stress tolerance and high mobility, allowing them to progress to a therapy-refractive state. To identify a critical molecule to regulate cancer stemness is indispensable to erratically cure cancer. In this study, we identified...

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Publicat a:Sci Rep
Autors principals: Lu, Ya-Ching, Cheng, Ann-Joy, Lee, Li-Yu, You, Guo-Rung, Li, Yan-Liang, Chen, Hsin-Ying, Chang, Joseph T.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435724/
https://ncbi.nlm.nih.gov/pubmed/28515423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02058-8
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