Oncolytic Herpes Simplex Virus Inhibits Pediatric Brain Tumor Migration and Invasion

Pediatric high-grade glioma (pHGG) and diffuse intrinsic pontine glioma (DIPG) are invasive tumors with poor survival. Oncolytic virotherapy, initially devised as a direct cytotoxic treatment, is now also known to act via immune-mediated mechanisms. Here we investigate a previously unreported mechan...

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Gepubliceerd in:Mol Ther Oncolytics
Hoofdauteurs: Cockle, Julia V., Brüning-Richardson, Anke, Scott, Karen J., Thompson, Jill, Kottke, Timothy, Morrison, Ewan, Ismail, Azam, Carcaboso, Angel M., Rose, Ailsa, Selby, Peter, Conner, Joe, Picton, Susan, Short, Susan, Vile, Richard, Melcher, Alan, Ilett, Elizabeth
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435599/
https://ncbi.nlm.nih.gov/pubmed/28547002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2017.04.002
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