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A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis
BACKGROUND: Melioidosis, caused by the flagellated bacterium Burkholderia pseudomallei, is a life-threatening and increasingly recognized emerging disease. Toll-like receptor (TLR) 5 is a germline-encoded pattern recognition receptor to bacterial flagellin. We evaluated the association of a nonsense...
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| Publicado no: | PLoS Negl Trop Dis |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5435357/ https://ncbi.nlm.nih.gov/pubmed/28475641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005587 |
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