Transcriptional activation of HIF-1 by a ROS-ERK axis underlies the resistance to photodynamic therapy

Photodynamic therapy (PDT), a promising treatment option for cancer, involves the activation of a photosensitizer (PS) by local irradiation with visible light. Excitation of the PS leads to a series of photochemical reactions and consequently the local generation of harmful reactive oxygen species (...

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Bibliographic Details
Published in:PLoS One
Main Authors: Lamberti, María Julia, Pansa, María Florencia, Vera, Renzo Emanuel, Fernández-Zapico, Martín Ernesto, Rumie Vittar, Natalia Belén, Rivarola, Viviana Alicia
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435305/
https://ncbi.nlm.nih.gov/pubmed/28545088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177801
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