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Differences in SpeB protease activity among group A streptococci associated with superficial, invasive, and autoimmune disease

The secreted cysteine proteinase SpeB is an important virulence factor of group A streptococci (GAS), whereby SpeB activity varies widely among strains. To establish the degree to which SpeB activity correlates with disease, GAS organisms were recovered from patients with pharyngitis, impetigo, inva...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ly, Anhphan T., Noto, John P., Walwyn, Odaelys L., Tanz, Robert R., Shulman, Stanford T., Kabat, William, Bessen, Debra E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435240/
https://ncbi.nlm.nih.gov/pubmed/28545045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177784
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