Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease

OBJECTIVES: To assess the neurobiological substrate of initial cognitive decline in Parkinson’s disease (PD) to inform patient management, clinical trial design, and development of treatments. METHODS: We longitudinally assessed, up to 3 years, 423 newly diagnosed patients with idiopathic PD, untrea...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Caspell-Garcia, Chelsea, Simuni, Tanya, Tosun-Turgut, Duygu, Wu, I-Wei, Zhang, Yu, Nalls, Mike, Singleton, Andrew, Shaw, Leslie A., Kang, Ju-Hee, Trojanowski, John Q., Siderowf, Andrew, Coffey, Christopher, Lasch, Shirley, Aarsland, Dag, Burn, David, Chahine, Lana M., Espay, Alberto J., Foster, Eric D., Hawkins, Keith A., Litvan, Irene, Richard, Irene, Weintraub, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435130/
https://ncbi.nlm.nih.gov/pubmed/28520803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175674
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