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Exportin-5 functions as an oncogene and a potential therapeutic target in colorectal cancer

OBJECTIVE: Dysregulated expression of microRNAs (miRNAs) has emerged as a hallmark feature in human cancers. Exportin-5 (XPO5), a karyopherin family member, is a key protein responsible for transporting precursor miRNAs from the nucleus to the cytoplasm. While XPO5 is one of the key regulators of mi...

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Bibliografische gegevens
Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Shigeyasu, Kunitoshi, Okugawa, Yoshinaga, Toden, Shusuke, Boland, C. Richard, Goel, Ajay
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435115/
https://ncbi.nlm.nih.gov/pubmed/27553833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1023
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