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Optimization of RGD-modified Nano-liposomes Encapsulating Eptifibatide

BACKGROUND: Eptifibatide (Integrilin) is an intravenous (IV) peptide drug that selectively inhibits ligand binding to the platelet GP IIb/IIIa receptor. It is an efficient peptide drug, however has a short half-life. Therefore, antithrombotic agents like eptifibatide are required to become improved...

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Bibliographic Details
Published in:Iran J Biotechnol
Main Authors: Bardania, Hassan, Shojaosadati, Seyed Abbas, Kobarfard, Farzad, Dorkoosh, Farid
Format: Artigo
Language:Inglês
Published: National Institute of Genetic Engineering and Biotechnology 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435030/
https://ncbi.nlm.nih.gov/pubmed/28959324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/ijb.1399
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