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Production by activated human T cells of interleukin 4 but not interferon-gamma is associated with elevated levels of serum antibodies to activating malaria antigens.

T cells play a crucial role in antibody-mediated and antibody-independent immunity against Plasmodium falciparum malaria. Therefore, a vaccine immunogen should include parasite-derived B- and T-cell epitopes capable of giving rise to protective responses in both systems. The P. falciparum antigen Pf...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Troye-Blomberg, M, Riley, E M, Kabilan, L, Holmberg, M, Perlmann, H, Andersson, U, Heusser, C H, Perlmann, P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54349/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2115172/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.14.5484
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