Humanized Mouse Model for Assessing the Human Immune Response to Xenogeneic and Allogeneic Decellularized Biomaterials

Current assessment of biomaterial biocompatibility is typically implemented in wild type rodent models. Unfortunately, different characteristics of the immune systems in rodents versus humans limit the capability of these models to mimic the human immune response to naturally derived biomaterials. H...

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Udgivet i:Biomaterials
Main Authors: Wang, Raymond M., Johnson, Todd D., He, Jingjin, Rong, Zhili, Wong, Michelle, Nigam, Vishal, Behfar, Atta, Xu, Yang, Christman, Karen L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434867/
https://ncbi.nlm.nih.gov/pubmed/28334641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.03.016
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