Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression

Response to antidepressant (AD) treatment may be a more polygenic trait than previously hypothesized, with many genetic variants interacting in yet unclear ways. In this study we used methods that can automatically learn to detect patterns of statistical regularity from a sparsely distributed signal...

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發表在:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Malki, Karim, Tosto, Maria Grazia, Mouriño‐Talín, Héctor, Rodríguez‐Lorenzo, Sabela, Pain, Oliver, Jumhaboy, Irfan, Liu, Tina, Parpas, Panos, Newman, Stuart, Malykh, Artem, Carboni, Lucia, Uher, Rudolf, McGuffin, Peter, Schalkwyk, Leonard C., Bryson, Kevin, Herbster, Mark
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434854/
https://ncbi.nlm.nih.gov/pubmed/27696737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32494
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