Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression

Response to antidepressant (AD) treatment may be a more polygenic trait than previously hypothesized, with many genetic variants interacting in yet unclear ways. In this study we used methods that can automatically learn to detect patterns of statistical regularity from a sparsely distributed signal...

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Vydáno v:Am J Med Genet B Neuropsychiatr Genet
Hlavní autoři: Malki, Karim, Tosto, Maria Grazia, Mouriño‐Talín, Héctor, Rodríguez‐Lorenzo, Sabela, Pain, Oliver, Jumhaboy, Irfan, Liu, Tina, Parpas, Panos, Newman, Stuart, Malykh, Artem, Carboni, Lucia, Uher, Rudolf, McGuffin, Peter, Schalkwyk, Leonard C., Bryson, Kevin, Herbster, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434854/
https://ncbi.nlm.nih.gov/pubmed/27696737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32494
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