Human NUMB6 Induces Epithelial-Mesenchymal Transition and Enhances Breast Cancer Cells Migration and Invasion

Mammalian NUMB is alternatively spliced generating four isoforms NUMB1-NUMB4 that can function as tumor suppressors. NUMB1-NUMB4 proteins, which normally determine how different cell types develop, are reduced in 21% of primary breast tumors. Our previous work has, however, indicated that two novel...

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I publikationen:J Cell Biochem
Huvudupphovsmän: Karaczyn, Aldona A., Adams, Tamara L., Cheng, Robert Y.S., Matluk, Nicholas N., Verdi, Joseph M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434706/
https://ncbi.nlm.nih.gov/pubmed/27302072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25628
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