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Tryptophan catabolism and immune activation in primary and chronic HIV infection

BACKGROUND: Kynurenine/Tryptophan ratio (KTR) is increased in HIV infection, and linked to immune activation. We hypothesized that early cART initiation results in lower KTR compared to late initiation. Furthermore, we hypothesized that KTR prior to cART is a predictor of the magnitude of subsequent...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Gelpi, Marco, Hartling, Hans J., Ueland, Per M., Ullum, Henrik, Trøseid, Marius, Nielsen, Susanne D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434617/
https://ncbi.nlm.nih.gov/pubmed/28511640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-017-2456-z
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